April 23 2020
… you spoil the game. Mike Caro
Vocabulary: ACE - Angiotensin Converting Enzyme inhibitor - a class of medications improving overall survival in patients with hypertension, coronary artery disease, heart failure, and kidney disease.
Zhang and co-authors published the article titled “Association of Inpatient Use of Angiotensin Converting Enzyme Inhibitors and Angiotensin II Receptor Blockers with Mortality Among Patients With Hypertension Hospitalized With COVID-19”.
This retrospective, multi-center study included 1128 adult patients with hypertension diagnosed with COVID-19, including 188 taking ACEI/ARB (ACEI/ARB group; median age 64 [IQR 55- 68] years; 53.2% men) and 940 without using ACEI/ARB (non-ACEI/ARB group; median age 64 [IQR 57- 69]; 53.5% men), who were admitted to nine hospitals in Hubei Province, China from December 31, 2019 to February 20, 2020.
Unadjusted mortality rate was lower in the ACEI/ARB group versus the non- ACEI/ARB group (3.7% vs. 9.8%; P = 0.01).
Conclusion: Among hospitalized COVID-19 patients with hypertension, inpatient use of ACEI/ARB was associated with lower risk of all-cause mortality compared with ACEI/ARB non-users.
Dr. Why: I wrote about this on the basis of common sense, not specific cohort analysis. The best one can do to survive is to be healthy,
Apr 22 The Study Of 5700 Patients